4H-thieno[3,4-c]pyrrole derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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5483117, 548453, A61K 31415, C07D40314

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active

053807421

ABSTRACT:
Pyrrole derivatives of formula: ##STR1## in which R.sub.1 represents a hydrogen or halogen atom, a linear or branched C.sub.1-6 alkyl group, a C.sub.3-6 alkenyl group, a C.sub.1-4 alkoxymethyl group, benzyl, a phenyl group optionally substituted by one or more halogen atoms or alkyl radicals, a CO.sub.2 R group in which R represents a linear or branched C.sub.1-4 alkyl radical, phenyl or benzyl, or a CONR'R" group in which R' and R" each represent, independently of one another, a hydrogen atom or a linear or branched C.sub.1-4 alkyl radical,

REFERENCES:
patent: 5190938 (1993-03-01), Badorc et al.
patent: 5276009 (1994-01-01), Muenster et al.
D. J. Zwanenburg et al., "Steric Inhibition of Intramolecular Cyclizations by ortho Substituents, The Synthesis of 1H,3H-Thieno[3,4-c]thiophene, Its 2,2-Dioxide, and 5-Ethyl-5,6-dihydro-4H-thieno[3,4-c]pyrrole," The Journal Of Organic Chemistry, vol. 34, No. 2, pp. 333-340, Feb. 1969.

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