4H-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives

Details 4H-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives 4H-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives

1988-01-20

1988-10-04

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 44, A61K 3138, C07D33374

Patent

active

047756918

ABSTRACT:
[2-Halo-10-oxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]acetic acids, for example of formula I ##STR1## wherein R.sub.1 is H or C.sub.1-4 alkyl and R.sub.2 is halogen, their physiologically-hydrolysable and -acceptable esters, and salts thereof. Such compounds, esters and salts possess valuable pharmaceutical, in particular anti-inflammatory, antipyretic and analgesic, properties.

REFERENCES:
patent: 4137323 (1979-01-01), Bastian
patent: 4183943 (1980-01-01), Bastian
patent: 4487778 (1984-12-01), Plummer
patent: 4496580 (1985-01-01), Martin et al.

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