4H-benzo(4,5)cyclohepta(1,2-B)thiophene derivatives

Details 4H-benzo(4,5)cyclohepta(1,2-B)thiophene derivatives 4H-benzo(4,5)cyclohepta(1,2-B)thiophene derivatives

1987-07-14

1988-04-26

Siegel, A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 44, A61K 3138, C07D33374

Patent

active

047405180

ABSTRACT:
.alpha.-[5H-dibenzo[a,d]cyclohepten-5-ylidene]-carboxylic acids e.g. of formula I ##STR1## wherein R.sub.1 is H, C.sub.1-4 alkyl or phenyl-(C.sub.1-4 alkyl), R.sub.2 is H or C.sub.1-4 alkyl and ring A is unsubstituted or halo- or hydroxy-substituted, as well as the physiologically-hydrolysable and -acceptable esters thereof have valuable pharmaceutical, in particular anti-inflammatory, antipyretic and analgesic properties.

REFERENCES:
patent: 4137323 (1979-01-01), Bastian

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