42-Epi-rapamycin and pharmaceutical compositions thereof

Details 42-Epi-rapamycin and pharmaceutical compositions thereof 42-Epi-rapamycin and pharmaceutical compositions thereof

1995-04-26

1996-06-11

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

540456, A61K 3155, C07D49604, C07D49614, C07D49104, C07D49114

Patent

active

055256104

ABSTRACT:
This invention comprises the compound of 42-Epimer Rapamycin of the following structural formula: ##STR1## as well as pharmaceutical compositions containing 42-Epi-Rapamycin and its use in methods for inducing immunosuppression and methods for treating transplantation rejection, graft vs. host disease, autoimmune diseases, diseases of inflammation, solid tumors, fungal infections, adult T-cell leukemia/lymphomas and hyperproliferative vascular disorders.

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