4β-1″-[(2″-substituted benzoyl)...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S468000, C549S298000

Reexamination Certificate

active

07087641

ABSTRACT:
The present invention provides a new class of compounds 4β-1″-[{2″-benzoyl substituted}anilino] podophyllotoxin exhibiting anti cancer activity and a process for preparing the same.

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patent: 6872841 (2005-03-01), Lee et al.
patent: 6878746 (2005-04-01), Monneret et al.
Cho et al., “Antitumor Agents 163 Three-Dimensional Quantitative Structure-Activity Relationship Study of 4′-0- Demethylepipodopyllotoxin Analogs Using the CoMFA/q2-GRS Approach,” Journal of Medicinal Chemistry, vol. 39, No. 7, 1996, pp. 1383-1395, XP-002222563.

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