4′-substituted nucleoside derivatives as inhibitors...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S050000, C514S051000, C514S934000, C514S004300

Reexamination Certificate

active

08071567

ABSTRACT:
The present invention relates to the use of nucleoside derivatives of formula Iawherein the symbols are as defined in the specification, and of pharmaceutically acceptable salts thereof and to pharmaceutical compositions containing such compounds.

REFERENCES:
patent: 3910885 (1975-10-01), Moffatt et al.
patent: 5155112 (1992-10-01), Storer
patent: 5449664 (1995-09-01), Verheyden et al.
patent: 5496546 (1996-03-01), Wang
patent: 2002/0055483 (2002-05-01), Watanabe et al.
patent: 0371366 (1990-06-01), None
patent: 0457326 (1991-11-01), None
patent: 0799834 (1997-10-01), None
patent: 06060688 (1994-03-01), None
patent: 7126282 (1995-05-01), None
patent: WO-9943691 (1999-09-01), None
patent: WO-0069876 (2000-11-01), None
Hans Maag, et al., “Synthesis and Anti-HIV Activity of 4′-Azido- and 4′ -Methoxynucleosides1”,Journal of Med. Chem., (1992), pp. 1440-1451, vol. 35.
J. G. Moffatt, outline of the synthesis of 4′-azidocytidine from chapter titled “Chemical Transformations of the Sugar Moiety of Nucleosides,” from bookNucleoside Analogues, (1979) p. 144 published by Plenum Press, New York and London.

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