4′-c-substituted-2-haloadenosine derivative

Details 4′-c-substituted-2-haloadenosine derivative 4′-c-substituted-2-haloadenosine derivative

2007-11-19

2009-12-01

Crane, Lawrence E (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S026700, C536S027140, C536S027610

Reexamination Certificate

active

07625877

ABSTRACT:
The present invention provides a 4′-C-substituted-2-haloadenosine derivative represented by the following formula [I], [II], or [III]:wherein X represents a halogen atom, R1represents an ethynyl group or a cyano group, and R2represents hydrogen, a phosphate residue, or a phosphate derivative residue. The present invention also provides a pharmaceutical composition containing the derivative and a pharmaceutically acceptable carrier therefor. The derivative is useful as a medicine for the treatment of Acquired Immune Deficiency Syndrome (AIDS).

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