4-Thioquinazoline derivatives as antiulcer agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544284, 544287, C07D40100, C07D23972, A61K 31505

Patent

active

048290696

ABSTRACT:
4-Thioquinazoline derivatives of formula (I) are provided. ##STR1## wherein R.sup.1 is a C.sub.1 -C.sub.6 alkylamino group, a phenyl group, a substituted phenyl group or a 5- or 6-membered heterocyclic group containing one or two N, O or S as a hetero atom or atoms, said heterocyclic group optionally being substituted or fused with a benzene ring; n is 1 or 2; or R.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.6 alkyl group, and pharmaceutically acceptable acid addition salts thereof. They are useful as antiulcer agents.

REFERENCES:
patent: 4349674 (1982-09-01), Freed et al.
patent: 4665075 (1987-05-01), Vandenberk et al.

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