4-Thio substituted-.DELTA..sup.2 cephalosporin intermediates

Details 4-Thio substituted-.DELTA..sup.2 cephalosporin intermediates 4-Thio substituted-.DELTA..sup.2 cephalosporin intermediates

1977-05-16

1978-05-23

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424246, C07D50120

Patent

active

040912167

ABSTRACT:
Cephalosporin intermediates of the formulas ##STR1## wherein R is lower alkyl, 2,2,2-trichloroethyl, diphenylmethyl, p-methoxybenzyl, or p-nitrobenzyl; R.sub.1 is lower alkyl or phenyl; R.sub.2 is hydrogen or acetoxy; R.sub.4 is methyl or ethyl; and R.sub.5 is hydrogen, methyl, or methoxy; are disclosed. Methods of reacting these intermediates to prepare antibacterially active cephalosporins are disclosed.

REFERENCES:
patent: 3849408 (1974-11-01), Dolfini
patent: 3941779 (1976-03-01), Slusarchyk et al.
patent: 3968109 (1976-07-01), Koster et al.

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