4-substituted pyrazoloquinoline derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546 82, A61K 3147, A61K 31475, C07D47106

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active

054591465

ABSTRACT:
Compounds of the formulas I and II ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.3, R.sub.4, R.sub.6, R.sub.8, and R.sub.9 are as set forth herein, are described. These compounds are useful as agents for treating patients afflicted with a herpes group virus. Certain of these compounds are also useful as antitumor agents.

REFERENCES:
patent: 3234142 (1966-02-01), Wolfrum
patent: 3790573 (1974-02-01), Blackburn
Ning, "Intromolecular Nitrene . . . ", J. Org Chem, vol. 42, No. 10, pp. 1791-1794, 1977, Dec. 1976.
Radl, "Synthesis of Some . . . ", Coll of Czech Chem Comm, 50(9), pp. 2010-2014, 1988.
Crenshaw et al, Journal of Medicinal Chemistry, 1976, vol. 19, No. 2, pp. 262-275.
Czechoslovak 34(3-4) pp. 119-122, (1985) and English translation thereof.
Stein et al, Jan. 1970, vol. (13) (1), pp. 153-155. J. Med. Chem.
BIOSIS/CAS Selects: Antiviral Agents Issue, No. 5, 108:55961t, 1988.
Collection Czech. Chem. Commun. (vol. 53) (1988), pp. 1812-1819.
Czech Pharmacy 429-432, (1984), vol. 33(10).
Chem Abstracts 756g vol. 61 of Belgium 632,758, published Oct. 21, 1963.
BIOSIS/CAS Selects Antiviral Agents Issue No. 6, (1989), 110:75486m.
CA2945 f abstract of Ger. 1,152,421, 1964.

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