4-substituted octahydroquinolizine analgesic compounds and octah

Details 4-substituted octahydroquinolizine analgesic compounds and octah 4-substituted octahydroquinolizine analgesic compounds and octah

1986-04-10

1987-12-29

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546138, A61K 31345, C07D45502

Patent

active

047161728

ABSTRACT:
Octahydroquinolizine and corresponding octahydroquinolizinium compounds of formulae (I) and (Va): ##STR1## where A is a 3 to 7 membered carbocyclic ring, R.sup.1 is a substituent, n is 0-2, x is 0-3, and Y is an anion. Also, pharmaceutical compositions for treating pain containing (I) and methods for synthesis and use as well as novel intermediates in the synthesis.

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