4-substituted azetidinones as precursors to 2-substituted-3-carb

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20508, C07D47700, C07D46300, C07D40906

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active

056567537

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.4, R.sup.5, R.sup.12, R.sup.16 and R.sup.17 are defined in the specification are provided. These compounds are useful as intermediates for the preparation of carbapenem antibacterials.

REFERENCES:
patent: 4350631 (1982-09-01), Christensen
patent: 5149802 (1992-09-01), Yoshioka
patent: 5177074 (1993-01-01), Allen, Jr.
Wasserman et al., Tetrahedron Letters, 25:3747-3750 (1984).
Bateson, "Recent Advances in Chemistry of .beta. Lactam Antibiotics", Special Publication #38, 1981, pp. 291-313.
Thara, J.A.C.S. 105, 7345 (1983).
Knierzinger, J. Chem Soc, Chem. Comm 1984, 9-11.
Hirai, Tet. Letters 24, 3251 (1983).

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