4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline

Details 4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline 4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline

1982-04-12

1983-07-05

Raymond, Richard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Cancer cell or component thereof

549 38, A61K 31385, C07D33906

Patent

active

043918182

ABSTRACT:
N-(1,3-dithiolan-2-ylidene)-4-alkylanilines having a hydroxy, alkoxy or alkanoyloxy substituent on the alkyl group are useful as anti-inflammatory agents, as analgesic agents and as antiasthmatic agents. The compounds involved can be prepared by the reaction of an appropriate 4-alkylaniline with a methyl(1,3-dithiolan-2-ylidene)sulfonium salt or with carbon disulfide and ethylene dibromide in the presence of a base.

REFERENCES:
patent: 4004019 (1977-01-01), Brand et al.
patent: 4060628 (1977-11-01), Enders et al.
patent: 4131683 (1978-12-01), Harrison et al.
patent: 4172941 (1979-10-01), Harrison et al.

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