Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1979-06-11
1985-08-27
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514425, 548465, 548548, C07D40302, C07D20740, A61K 3140
Patent
active
045379025
ABSTRACT:
Novel 4-substituted-3-hydroxy-3-pyrroline-2,5-diones are disclosed which inhibit glycolic acid oxidase and thus are useful in the treatment and prevention of calcium oxalate renal lithiasis.
REFERENCES:
patent: 3340263 (1967-09-01), Staehelin et al.
Cragoe, Jr. Edward J.
Rooney Clarence S.
Williams Haydn W. R.
Hollrah Glennon H.
Merck & Co. , Inc.
Merck Sharp & Dohme (I.A.) Corp.
Speer Raymond M.
Springer D. B.
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