4-Substituted 3,5-morpholinediones

Details 4-Substituted 3,5-morpholinediones 4-Substituted 3,5-morpholinediones

1980-08-08

1981-12-15

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D41306

Patent

active

043060633

ABSTRACT:
Novel (2-amino-2-oxoethoxy)acetic acid compounds and antisecretory compositions and methods employing (2-amino-2-oxoethoxy)acetic acid compounds are disclosed. The (2-amino-2-oxoethoxy)acetic acid compounds are also useful as cardiotonic agents and as calcium binding agents; certain of the compounds are also useful for their calcium transport properties. Novel 4-substituted 3,5-morpholinediones intermediates in the preparation of certain of the (2-amino-2-oxoethoxy)acetic acid compounds and further useful as antisecretory agents are also disclosed.

REFERENCES:
patent: 3563986 (1971-02-01), Frankus et al.
patent: 3770820 (1973-11-01), Ackerman
Baron et al., Chem. Abstracts, vol. 70 (1969) No. 3978l.

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