4-Substituted-2-oxoazetidine compounds and processes for the pre

Details 4-Substituted-2-oxoazetidine compounds and processes for the pre 4-Substituted-2-oxoazetidine compounds and processes for the pre

1981-08-27

1983-05-17

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452T, 2602454, 2603309, 544 90, C07D40304, C07D49810, C07D20508, C07D48704

Patent

active

043839452

ABSTRACT:
This invention relates to novel 4-substituted-2-oxoazetidine compounds and salts thereof, which are useful intermediates in the preparation of antibiotics having the fundamental skeleton of Thienamycin, which compounds are of the formula: ##STR1## in which R.sup.1 is halogen, isocyano, hydroxy(lower)alkyl or protected hydroxy(lower)alkyl,

REFERENCES:
patent: 4115383 (1978-09-01), Cooper
patent: 4153714 (1979-05-01), Ponsford
patent: 4187221 (1980-02-01), Micetich
patent: 4273709 (1981-06-01), Christensen
D. Johnston et al., Journal of the American Chemical Society, vol. 100, p. 313 (1978).
L. Cama et al., Journal of the American Chemical Society, vol. 100, p. 8006, (1978).
T. Salzmann et al., Journal of the American Chemical Society, vol. 102, p. 6161.
H. Onoue et al., Tetrahedron Letters No. 40, p. 3867 (1979).
P. H. Bentley et al., Journal of the Chemical Society Chemical Communication, p. 278 (1974).
D. I. John et al., Journal of the Chemical Society Chemical Communication, p. 345 (1979).

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