4-Substituted 2-iminoimidazolidine compounds

Details 4-Substituted 2-iminoimidazolidine compounds 4-Substituted 2-iminoimidazolidine compounds

1980-05-05

1981-09-08

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544364, 544370, 546150, 546210, 546278, 548315, C07D41306, C07D40106, C07D40306, C07D23346

Patent

active

042885914

ABSTRACT:
This invention provides a novel class of 2-iminoimidazolidines which include 4-substituted derivatives such as 4-(2-chloroethyl)-1-methyl-2-methylimino-3-phenyl imidazolidine fumarate: ##STR1## This illustrated 4-substituted 2-iminoimidazolidine compound exhibits cardiovascular hypotensive, hypoglycemic (glucose tolerance, and sugar cataract) and anti-inflammatory (pleural effusion) pharmacological activities in test animals.

REFERENCES:
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patent: 3793317 (1974-02-01), Beaman et al.
patent: 3979380 (1976-09-01), Failli et al.
patent: 4058616 (1977-11-01), Kummer et al.
patent: 4080503 (1978-03-01), Kummer et al.
patent: 4181722 (1980-01-01), Beranger et al.

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