4-Substituted-2-hydroxybutanoates and a process for producing th

Details 4-Substituted-2-hydroxybutanoates and a process for producing th 4-Substituted-2-hydroxybutanoates and a process for producing th

1992-11-16

1994-06-28

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

558332, 558352, 558441, 560184, C07C25503, C07F 506

Patent

active

053248520

ABSTRACT:
The present invention provides an optically active 4-substituted-2-hydroxybutanoate represented by the general formula: ##STR1## wherein X is Cl, Br, I or Cn, R is alkyl, and * shows an asymmetric carbon.
The compounds which are useful as starting materials for medical agents, are obtained by a process comprising ring-opening optically active .alpha.-hydroxy-.gamma.-butyrolactone and esterifying the compound obtained.

REFERENCES:
patent: 4335255 (1982-06-01), Krespan
patent: 4348535 (1982-08-01), Schmidt
patent: 4495190 (1985-01-01), Hagberg et al.
Chem. Abstracts, vol. 97, No. 3; 23301r (1982).
Chem. Abstracts, vol. 102, No. 23;204243r (1985).

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