4-substituted 17.beta.-(cyclopropylamino)androst-5-en-3.beta.-ol

Details 4-substituted 17.beta.-(cyclopropylamino)androst-5-en-3.beta.-ol 4-substituted 17.beta.-(cyclopropylamino)androst-5-en-3.beta.-ol

1989-08-15

1990-10-30

Lipovsky, Joseph A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514177, 552522, A61K 3156, A61K 3166

Patent

active

049668986

ABSTRACT:
This invention is directed to 4-substituted 17.beta.-(cyclopropylamino)androst-5-en-3.beta.-ol and related compounds and also to a method for using such compounds in the treatment of androgen-dependent disorders. The compounds are prepared by the hydride reduction of an appropriate steroidal imine or enamine.

REFERENCES:
patent: 3097200 (1963-07-01), Kinel
patent: 3107254 (1963-10-01), Lednicer
Chemical Abstracts: vol. 111; 7670n, (1989).
Davis et al., J. Chem. Soc., C, Org., 19, 1688, (1966).
B. J. Taylor, M. S. Thesis, Massachusetts Institute of Technology, 1985, pp. 2, 24-26.

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