4-Substituted-1,3-dithiolan-2-ylidene malonates and pharmaceutic

Details 4-Substituted-1,3-dithiolan-2-ylidene malonates and pharmaceutic 4-Substituted-1,3-dithiolan-2-ylidene malonates and pharmaceutic

1977-02-08

1978-09-05

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26029368, 26032635, 260307FA, 260327M, 424267, 424272, 424274, 424277, 544 89, 544145, C07D33906, C07D41302, A61K 3140, A61K 31535

Patent

active

041120892

ABSTRACT:
A 1,3-dithiolan-2-ylidene malonate derivative having the formula, ##STR1## wherein R.sup.1 and R.sup.2, which may be same or different, represent individually a C.sub.1 -C.sub.4 alkyl group; and R.sup.3 represents a chloromethyl group, a phenyl group, a group of the formula ##STR2## (where R.sup.4 and R.sup.5 represent individually a C.sub.1 -C.sub.4 alkyl group, or may form, in combination, a lower alkylene group which is sometimes intercepted by an oxygen atom), or a group of the formula ##STR3## (where M represents a hydrogen atom or a salt-forming residue; and A represents a lower alkylene group, a lower alkylene group, a phenylene group or a cyclohexenylene group), has effects of stimulating, improving and recovering the functions of livers, and can prevent, alleviate and cure various liver damages of humans and animals when administered thereto either orally or parenterally.

REFERENCES:
patent: 3761596 (1973-09-01), Taninaka et al.
patent: 3856816 (1974-12-01), Taninaka et al.

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