4-pyridyl-1,3-dioxane derivatives

Details 4-pyridyl-1,3-dioxane derivatives 4-pyridyl-1,3-dioxane derivatives

1993-06-21

1995-03-28

Henley, III, Raymond J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40504

Patent

active

054018498

ABSTRACT:
The invention concerns pharmaceutically useful 1,3-dioxane alkenoic acid derivatives of formula VII and formula XI containing a pyridyl moiety at position 4 of the dioxane ring and in which the groups at positions 2, 4 and 5 have cis-relative stereochemistry, wherein X is hydrogen, alkoxy or hydroxy, Y is vinylene, n is 1 or 2, A.sup.1 is alkylene, R.sup.1 is a variety of substituents defined hereinafter, Ra and Rb are independently methyl or ethyl, R.sup.2 is hydroxy, a physiologically acceptable alcohol residue or alkanesulphonamido, and the pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 4554011 (1985-11-01), Loh
patent: 4567197 (1986-01-01), Brewster et al.
patent: 4668698 (1987-05-01), Brewster et al.
patent: 4704399 (1987-11-01), Main
patent: 4723037 (1988-02-01), Harris
patent: 4735963 (1988-04-01), Matassa et al.
patent: 4736057 (1988-05-01), Guildford et al.
patent: 4745198 (1988-05-01), Brewster et al.
patent: 4772625 (1988-09-01), Brewster
patent: 4775684 (1988-10-01), Smithers
patent: 4775685 (1988-10-01), Brewster
patent: 4803220 (1989-02-01), Brewster et al.
patent: 4806563 (1989-02-01), Smithers
patent: 4822815 (1989-04-01), Brown et al.
patent: 4824858 (1989-04-01), Brown et al.
patent: 4831046 (1989-05-01), Brown et al.
patent: 4845120 (1989-07-01), Brown et al.
patent: 4895962 (1990-01-01), Brewster
patent: 4895963 (1990-01-01), Brewster
patent: 4900846 (1990-02-01), Harris
patent: 4902712 (1990-02-01), Smithers
patent: 4908380 (1990-03-01), Brewster et al.
patent: 4921866 (1990-05-01), Brewster et al.
patent: 4921979 (1990-05-01), Smithers
patent: 4925869 (1990-05-01), Smithers
patent: 5047412 (1991-09-01), Brown et al.
patent: 5053415 (1991-10-01), Brewster et al.
patent: 5072008 (1991-12-01), Harris
patent: 5126368 (1992-06-01), Smithers
patent: 5166377 (1992-11-01), Brewster et al.
patent: 5169974 (1992-12-01), Harris et al.
patent: 5219874 (1993-06-01), Faull et al.
C. W. Thornber; Isoterism and Molecular Modification in Drug Design (1979).

Affiliated with

Also associated with

Rating

4-pyridyl-1,3-dioxane derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-pyridyl-1,3-dioxane derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-pyridyl-1,3-dioxane derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2251415