4-pyridinyl-n-acyl-l-phenylalanines

Details 4-pyridinyl-n-acyl-l-phenylalanines 4-pyridinyl-n-acyl-l-phenylalanines

2005-07-12

2005-07-12

Richter, Johann (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S300000, C546S268700, C546S269700, C546S269100, C546S271100, C546S271400, C546S272100, C546S272400, C546S272700, C546S276400, C546S280100, C546S280400, C546S282100, C546S301000, C546S303000, C546S194000, C544S066000, C544S131000, C544S360000

Reexamination Certificate

active

06916933

ABSTRACT:
Compounds of Formula I have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4 and are useful for treating disease whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4.

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Ca 89:5710 reference, “Substituent effect on selectivity in photoisomerization of 4-pyrones and 4-pyridones”, p. 492, 1978.

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