4-Pyridine carbonyl phenyl 1,2,4 triazoles

Details 4-Pyridine carbonyl phenyl 1,2,4 triazoles 4-Pyridine carbonyl phenyl 1,2,4 triazoles

1975-07-03

1977-08-23

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, 424263, 424267, 260256, 260 4Q, 260268H, 26029369, 2602948R, 260296R, 544131, C07D41314, A61K 31535

Patent

active

040441296

ABSTRACT:
A novel triazole derivative of the general formula (I): ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, represent alkyl group or aralkyl group and one of R.sup.1 and R.sup.2 may be hydrogen atom, or R.sup.1 and R.sup.2 form a heterocyclic ring together with the nitrogen atom adjacent thereto; R.sup.3 represents hydrogen atom or a hydrocarbon residue; R.sup.4 represents hydrogen atom or a lower alkyl group; Py represents a pyridyl group; and the ring A is either unsubstituted or substituted by halogen atom, nitro, alkyl, alkoxy or trifluoromethyl group, and pharmaceutically acceptable acid addition salts thereof are found to be useful as medicine in human and animal therapy, as these compounds act on the central nervous as for example, muscle relaxants, anticonvulsants, sedatives, minor tranquilizers, etc.

REFERENCES:
patent: 3646055 (1972-02-01), Hester
patent: 3749733 (1973-07-01), Hester
patent: 3813412 (1974-05-01), Gall et al.
patent: 3856792 (1974-12-01), Hester
patent: 3879406 (1975-04-01), Sternbach et al.

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