4-Pyridinamine derivatives

Details 4-Pyridinamine derivatives 4-Pyridinamine derivatives

1979-06-22

1981-01-06

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424263, C07D21338

Patent

active

042438080

ABSTRACT:
Novel 4-pyridinamine derivatives having the formula ##STR1## and their pharmaceutically acceptable acid addition salts (wherein A is C.sub.1 to C.sub.4 alkylene, each of B.sub.1 and B.sub.2, together with the two carbon atoms joined thereto, forms arylene or heteroarylene, R.sub.3 and R.sub.4 are independently hydrogen or lower alkyl and n is 0 or 1) are described. They show CNS activity and may be used as anti-depressant drugs.

REFERENCES:
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Kaye et al., Journal of Amer. Chem. Soc., vol. 74, pp. 403-407 (1952).
Villani et al., Journal of the Amer. Chem. Soc., vol. 73, pp. 5916-5917 (1951).
Carpenedo et al., Chem. Abstracts, vol. 73, p. 236, 108061s (1970).
Mndzhoyan et al., Chem. Abstracts, vol. 52, 4641b (1958).

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