4-Pregnene-derivatives, a process for their preparation, composi

Details 4-Pregnene-derivatives, a process for their preparation, composi 4-Pregnene-derivatives, a process for their preparation, composi

1981-11-17

1983-09-13

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

26023955D, A61K 3158

Patent

active

044042000

ABSTRACT:
The invention refers to compounds having anti-inflammatory activity, characterized by the formula ##STR1## in the form of a stereoisomeric mixture or an epimer of the R or S type regarding the orientation of the substituents at the carbon atom in position 22, in which formula A is n-propyl or n-butyl and Z is hydroxyl or hydroxyl esterified with a fatty acid with a straight or branched hydrocarbon chain having 1-5 carbon atoms.
The invention also refers to a process for the preparation of these compounds, a pharmaceutical preparation containing one of the compounds and a method for the treatment and control of inflammatory conditions.

REFERENCES:
patent: 2990401 (1961-06-01), Bernstein et al.
patent: 3048581 (1962-08-01), Fried
patent: 3549498 (1970-12-01), Diassi et al.
patent: 3928326 (1975-12-01), Brattsand et al.
patent: 3996359 (1976-12-01), Brattsand et al.

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