Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-03-06
2007-03-06
Desai, Rita (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S317000, C546S192000, C546S207000
Reexamination Certificate
active
10477633
ABSTRACT:
Compounds of general formula IR1is selected from any one of phenyl, pyridinyl, thienyl, furanyl, imidazolyl, pyrrolyl, triazolyl, thiazolyl, and pyridine N-oxide; where each R1phenyl ring and R1heteroaromatic ring may optionally and independently be further substituted by 1, 2 or 3 substituents selected from straight and branched C1–C6alkyl, NO2, CF3, C1–C6alkoxy, chloro, fluoro, bromo, and iodo. The substitutions on the phenyl ring and on the heteroaromatic ring may take place in any position on said ring systems; are disclosed and claimed in the present application, as well as salts and pharmaceutical compositions comprising the novel compounds and their use in therapy, in particular in the management of pain, anxiety or functional gastrointestinal disorders.
REFERENCES:
patent: 4091096 (1978-05-01), Beck et al.
patent: 4126689 (1978-11-01), Sanczuk et al.
patent: 4252812 (1981-02-01), Welch
patent: 4460586 (1984-07-01), Berthold
patent: 4680296 (1987-07-01), Manoury et al.
patent: 5118693 (1992-06-01), Toth et al.
patent: 5132303 (1992-07-01), Toth et al.
patent: 5132309 (1992-07-01), Toth et al.
patent: 5854245 (1998-12-01), Duggan et al.
patent: 6153626 (2000-11-01), Pelcman et al.
patent: 6399635 (2002-06-01), Pelcman et al.
patent: 6455545 (2002-09-01), Delorme et al.
patent: 6552036 (2003-04-01), Boyd et al.
patent: 6556387 (2003-04-01), Misso et al.
patent: 6756387 (2004-06-01), Brown et al.
patent: 28 22 465 (1978-11-01), None
patent: 206 677 (1989-08-01), None
patent: WO 98/28270 (1998-07-01), None
patent: WO 98/28275 (1998-07-01), None
patent: WO 99/33806 (1999-07-01), None
patent: WO 99/45925 (1999-09-01), None
patent: WO 0146263 (2001-06-01), None
Wei et al, N,N-diethyl-4-(phenylpiperidine-4-ylidenemethyl0benzamide .. J. Of Med. Chem. 2000, vol. 43, 3895-3905.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; 1995, Wang, et al: “Opioid delta. receptor . . . and 4-(methoxymethyl)fentanyl”; Database Accession No. 1995:857886.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Deruiter, et al: “Investigation of the synthesis . . . 1-substituted 4-(propananilido)perhydroazepines”, Database Accession No. 1992:612296, 1992.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Ferrand, et al: “Synthesis of New 1,2,3-triazin-4-ones as Potential Antidepressants”, Database Accession No. 1988:150431, 1988.
Database ChemABE ‘Online’, CAS, Columbus, Ohio, US; Adachi, et al: “Aminohaloborane in organic synthesis. IX. Exclusive . . . N-monoaminoalkylanilines”, Database Accession No. 1987:49715, 1987.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Takai, et al: “Synthesis and Pharmacological Evaluation . . . Heterocyclic Rings at the 4-position”, Database Accession No. 1985:578235, 1985.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Sugasawa, et al: “1-Azacycloalkyl-1, 4-Benzodiazepin-2-ones with antianxiety- antidepressant actions”, Database Accession No. 1985:437458, 1985.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Zhu, et al: “Studies on Potent Analgesics. I. Synthesis . . . Derivatives”, Database Accession No. 1981:550311, 1981.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Burkartsmaier, et al: “Potential analgesics, IX: Synthesis . . . acid derivatives”, Database Accession No. 1979:54780, 1979.
Database ChemABS ‘Online’, CAS, Columbus, Ohio, US; Obase, et al: “New antihypertensive agents. III. Synthesis and . . . at the 4-position”, Database Accession No. 1984:120835, 1984.
Brown William
Griffin Andrew
Walpole Christopher
Astrazeneca AB
Cozen O'Connor P.C.
Desai Rita
Shen Jianzhong
LandOfFree
4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-(phenyl-(piperidin-4yl)-amino)-benzamide derivatives and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3788063