4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives

Details 4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives 4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives

1979-08-31

1981-04-14

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544330, 544332, A61K 31505, C07D23914, C07D23916

Patent

active

042619955

ABSTRACT:
Certain 1,4,5,6-tetrahydropyrimidine compounds which are substituted with an amino, amido or carbamate at the 2-position, with an optionally substituted phenyl at the 5-position or at the 4-position when there is no alkyl at the 1-position and optionally a lower alkyl at the 1-position when the phenyl is at the 5-position are useful as CNS agents and as antihypertensives.

REFERENCES:
patent: 3655895 (1972-04-01), Lucas et al.
patent: 3822262 (1974-07-01), Bream et al.
patent: 4088771 (1978-05-01), Roszkowski et al.
patent: 4129661 (1978-12-01), Roszkowski et al.

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