4-Phenyl-1,3-benzodioxans

Details 4-Phenyl-1,3-benzodioxans 4-Phenyl-1,3-benzodioxans

1975-08-15

1977-11-01

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029358, 2603265CA, 260268BQ, 260268BC, 42424854, 424250, 42424856, 424267, 424274, 4242484, 424278, 26032634, 544148, C07D31908, C07D40506, C07D40512

Patent

active

040565408

ABSTRACT:
Substituted 2-aminomethyl-4-phenyl-1,3-benzodioxans and derivatives thereof have been found to possess valuable anticonvulsant and antiarrhythmia activity in mammals. For example, cis-6-chloro-2-methylaminomethyl-4-phenyl-1,3-benzodioxan hydrochloride possesses potent anticonvulsant activity while cis-2-isopropylaminomethyl-4-phenyl-1,3-benzodioxan hydrochloride has potent antiarrhythmia activity.

REFERENCES:
patent: 2993909 (1961-07-01), Lo
patent: 3117978 (1964-01-01), Biel et al.
patent: 3149108 (1964-09-01), Koo et al.
patent: 3484448 (1969-12-01), Kramer
Dawksas, Chem. Abst. 71:12438e (1969).
Geigy, Chem. Abst. 57:16629c (1962).

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