4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compos

Details 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compos 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compos

1994-09-29

1995-09-12

Haley, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514521, 558426, A61K 31275, C07C25546

Patent

active

054496870

ABSTRACT:
Novel compounds of Formulas (I) and (II) ##STR1## are described herein. These compounds inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV.

REFERENCES:
patent: 4795757 (1989-01-01), Regan et al.
Chemical Abstracts, vol. 113, No. 1, Abstract 5823s, 1990.

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