Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Reexamination Certificate
2008-09-16
2008-09-16
Witherspoon, Sikarl A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
C562S496000, C514S521000, C514S559000, C514S561000, C514S599000, C558S410000
Reexamination Certificate
active
11226645
ABSTRACT:
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
REFERENCES:
patent: 4125732 (1978-11-01), McEvoy et al.
patent: 2003/0225158 (2003-12-01), Auerbach et al.
patent: 10195057 (1998-07-01), None
patent: WO 9728115 (1997-08-01), None
patent: WO 02/062774 (2002-08-01), None
patent: WO 02/100813 (2002-12-01), None
Oliver, B. et al., “Differential Expression of Peroxisome Proliferator-Activated Receptors (PPARs): Tissue Distribution of PPAR-α, -β, and -γin the Adult Rat.”Endocrinology, 1996, 354-366, 137, No. 1.
Boden, G. “Free Fatty Acids, Insulin Resistance, and Type 2 Diabetes Mellitus.”PAAP, 1999, 241-248, vol. 111, No. 3.
Leibowitz, M. D. et al., “Activation of PPARδ alters lipid metabolism in db/db mice.”FEBS, 2000, 333-336, vol. 473.
PCT International Search Report, dated Jun. 3, 2006 for PCT Appln. No. PCT/US2005/032938 which relates to U.S. Appl. No. 11/226,645, filed Sep. 14, 2005.
Written Opinion on the International Searching Authority for PCT Application No. PCT/US/2005/032938.
DeAngelis Alan
Demarest Keith
Kuo Gee-Hong
Pelton Patricia
Wang Aihua
Janssen Pharmaceutica N.V.
Witherspoon Sikarl A
LandOfFree
4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3920168