4-oxoquinoline-3-carboxylic acid derivatives and their use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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540470, 540481, 540541, 540575, 540597, 544229, 544363, 546 13, 546156, A61K 31495, C07D40104

Patent

active

050735560

ABSTRACT:
Compounds of formula (I): ##STR1## (in which: R.sup.1 represents fluorinated methoxy; R.sup.2 represents a nitrogen-containing heterocyclic group and R.sup.3 represents hydrogen or amino) and pharmaceutically acceptable salts, esters and amides thereof are valuable antibacterial agents, which may be prepared by reacting a compound similar to that of formula (I) but in which R.sup.2 is replaced by a halogen atom with a compound providing the required group R.sup.2.

REFERENCES:
patent: 4803205 (1989-02-01), Bridges et al.
patent: 4851418 (1989-07-01), Sanchez
patent: 4874764 (1989-10-01), Weda et al.
patent: 4894458 (1990-01-01), Masuzawa et al.

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