4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof

Details 4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof 4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof

1987-09-18

1990-05-01

Sneed, H. M. S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514247, C07D45502

Patent

active

049218573

ABSTRACT:
This invention relates to a method of treating bacterial infections with 4-oxo-4H-quinolizine-3-carboxylic acids and derivatives thereof. This invention further relates to pharmaceutical compositions that are useful in the treatment of bacterial infections.

REFERENCES:
patent: 4479947 (1984-10-01), Christensen
patent: 4650804 (1987-03-01), Kitaura et al.
patent: 4698349 (1987-10-01), Kitaura et al.
Kato et al., "Synthesis of Methylpyridine Derivatives XVII" Chem. Pharm. Bull. 22(4): 744-751 (1974).
Y. Sato, "The Synthesis of Lupine Alkaloids II, The Syntheis of 1-(.alpha.-Piperidyl)quinolizidine," Pharm. Bull., 5, 412-416 (1957).
G. Buchmann & W. Duchna, "Beitragzur Synthese von 1,3-disubstituierten 4H-Chinolizonen-(4)auf Basis Pyridyl-2-acetonitril," Pharmazie, 23, 301-303(1968)(Ger.).

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