Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1979-03-12
1980-09-16
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 17R, A61K 3171, C07H 1522
Patent
active
042230241
ABSTRACT:
4"-O-alkylgentamicins and sagamicins represented by the formula: ##STR1## wherein R.sub.1 is hydrogen or methyl: R.sub.2 is hydrogen or methyl; R.sub.3 is hydrogen or hydroxy; R.sub.4 is hydroxy when R.sub.3 is hydrogen and hydrogen when R.sub.3 is hydroxy; and R.sub.5 is loweralkyl; and the pharmaceutically acceptable salts thereof, intermediates therefor, and compositions and methods employing the potent antibiotics of this invention.
REFERENCES:
patent: 4044123 (1977-08-01), Daniels et al.
patent: 4055715 (1977-10-01), Tomioka et al.
DeVault Robert L.
McAlpine James B.
Abbott Laboratories
Brown Johnnie R.
Fato Gildo E.
Niblack Joyce R.
Niblack Robert L.
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