Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1982-06-25
1984-05-15
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
548544, C07D207416, C07D40510, A61K 3140
Patent
active
044487860
ABSTRACT:
Novel 4-substituted-3-hydroxy-3-pyrroline-2,5-diones are disclosed which inhibit glycolic acid oxidase and thus are useful in the treatment and prevention of calcium oxalate kidney stone formation. A novel process for their preparation is also disclosed.
Cragoe, Jr. Edward J.
Rooney Clarence S.
Williams Haydn W. R.
Arther Thomas E.
Coughlan, Jr. Paul M.
Merck & Co. , Inc.
Speer Raymond M.
Springer D. B.
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