Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-03-20
1979-05-22
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2603458R, 2603457R, 424177, 424118, 424283, C07C10352
Patent
active
041559029
ABSTRACT:
This invention provides 4-N-acylfortimicin B derivatives of the structure ##STR1## wherein R is acyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, or substituted aminoacyl of the formula ##STR2## where R.sup.1 is an acyl radical derived from an amino acid or a short peptide, and the pharmaceutically acceptable salts thereof.
The compounds are useful as intermediates for preparing 4-N-alkyl or substituted alkylfortimicin B derivatives. In addition to their utility as intermediates, some of the compounds of this invention are also useful as antimicrobial agents.
REFERENCES:
patent: 3931400 (1976-01-01), Nara et al.
patent: 3976768 (1976-08-01), Nara et al.
Nara, Takashi, et al., Chem. Abst. 84, 1976 p. 162885d.
Kurath Paul
Martin Jerry R.
Tadanier John S.
Abbott Laboratories
Fato Gildo E.
Niblack Robert L.
Phillips Delbert R.
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