4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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424180, 536 18, A61K 3171, C07H 1522

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active

042140790

ABSTRACT:
Fortimicin AL derivatives represented by the formula: ##STR1## wherein: R and R.sub.1 are the same or different members of the group consisting of hydrogen, acyl, aminoacyl, diaminoacyl, N-loweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl, loweralkyl, aminoloweralkyl, diaminoloweralkyl, hydroxyloweralkyl, N-loweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl, N-loweralkylaminohydroxyloweralkyl, N,N-diloweralkylaminohydroxyloweralkyl and the pharmaceutically acceptable salts thereof, with the limitation that R and R.sub.1 each cannot be hydrogen. The compounds are useful as anti-baterial agents.

REFERENCES:
patent: 4091032 (1978-05-01), Tadanier et al.
patent: 4124756 (1978-11-01), Martin et al.

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