4-morpholinyl-1H-indoles, pharmaceutical compositions and use

Details 4-morpholinyl-1H-indoles, pharmaceutical compositions and use 4-morpholinyl-1H-indoles, pharmaceutical compositions and use

1986-12-12

1987-10-13

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514233, 514234, 514236, 514237, 514238, 544143, A61K 31535, C07D41302

Patent

active

046999078

ABSTRACT:
Novel racemic mixtures and optical isomers of 4-morpholinyl-1H-indoles of the formula: ##STR1## wherein R and R.sub.1 are individually selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and R.sub.2 is selected from the group consisting of hydroxymethyl, alkylthiomethyl of 1 to 3 alkyl carbons, cyanomethyl and carboxy optionally esterified with an aliphatic alcohol of 1 to 5 carbon atoms or optionally amidified with an amine of the formula ##STR2## R.sub.3 is alkyl of 1 to 4 carbon atoms and R.sub.4 is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having the ability to activate neurons and to protect the same against ischemic or anoxic aggressions.

REFERENCES:
Clark, Chemical Abstracts, vol. 100, No. 6427z (1984).

Affiliated with

Also associated with

Rating

4-morpholinyl-1H-indoles, pharmaceutical compositions and use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-morpholinyl-1H-indoles, pharmaceutical compositions and use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-morpholinyl-1H-indoles, pharmaceutical compositions and use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-411550