4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid produced

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435156, 435877, 568763, 568801, C12P 742, C12R 140

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active

046346686

ABSTRACT:
The present invention provides a process for the production of p-cresol in a quantitative yield, which involves the acidification of an aqueous solution of 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid under ambient conditions of temperature and pressure to cause spontaneous decomposition of the starting material to p-cresol. The aqueous solution of 4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid is produced by microbiological conversion of p-xylene with Pseudomonas putida Biotype A strain ATCC 39119.

REFERENCES:
patent: 2727926 (1955-12-01), Kaeding et al.
patent: 4071398 (1978-01-01), Baierl
Davey, et al., Journal of Bacteriology, vol. 19, No. 3, 1974, (pp. 923-929).
Reiner, et al., Biochemistry, vol. 10, No. 13, 1971, pp. 2530-2536.

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