Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-07-01
1993-12-14
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549417, A01N 4316, C07D30910
Patent
active
052703347
ABSTRACT:
Novel antibiotic substances, including novel natural products, having the general formula ##STR1## wherein R.sub.1 and R.sub.2 are as defined herein, are disclosed. These compounds have been found to be cytochrome P450 inhibitors.
REFERENCES:
patent: 4952604 (1990-08-01), Hensens et al.
Journal of Medicinal Chemistry, vol. 32, No. 10 (Oct. 1989) pp. 2231-2239.
Schwartz et al., Journal of Antibiotics, vol. 44, No. 5 (May 1991), pp. 463-471.
Ermann Peter H.
O'Sullivan Joseph
Phillipson Douglas W.
Straub Henner
Chan Nicky
E. R. Squibb & Sons Inc.
Furman Jr. Theodore R.
Park Ellen K.
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