4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che

Details 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che

1978-09-25

1980-01-08

Tovar, Jose

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424250, 544388, C07D24124, A61K 31495

Patent

active

041828720

ABSTRACT:
Compounds of the formula ##STR1## wherein R is hydrogen (lower)alkyl, phen(lower)alkyl, benzoyl(lower)alkyl, or p-halobenzoyl(lower)alkyl; R.sup.1 is hydrogen or (lower)alkyl; R.sup.2 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, trifluoromethyl, or amino in the 7-, 8-, or 9-position; R.sup.3 is hydrogen, or (lower)alkyl; and R.sup.4 is hydrogen, (lower)alkyl, (lower)alkoxy, chlorine, fluorine, or trifluoromethyl in the 7-, 8-, or 9-position; or the non-toxic acid addition salts thereof; exert a hypotensive effect in hypertensive animals. Also disclosed are chemical intermediates, including 4-(lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acids.

REFERENCES:
patent: 4032639 (1977-06-01), Freed et al.
patent: 4089958 (1978-05-01), Freed et al.
patent: 4138567 (1979-02-01), Freed et al.

Affiliated with

Also associated with

Rating

4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-(Lower)alkyl-1-(o-nitrophenyl)piperazine-2-carboxylic acid che will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1941447