Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-12-19
1992-04-28
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514378, A61K 31535, A61K 3142
Patent
active
051089998
ABSTRACT:
This invention is directed to compounds of the formula (I): ##STR1## wherein R.sup.1 is --OR.sup.4 (where R.sup.4 is hydrogen, lower alkyl, lower hydroxyalkyl, phenyl, phenyl-lower-alkyl, or --(CH.sub.2).sub.n Y where n is an integer from 1 to 4 and Y is morpholino, --SR.sup.5, --C(O)OR.sup.5, --C(O)N(R.sup.6).sub.2, --N(R.sup.6).sub.2, or --N.sup.+ (R.sup.6).sub.3 X.sup.-, in which R.sup.5 is lower alkyl, each R.sup.6 is independently selected from hydrogen or lower alkyl, and X is halogen)
REFERENCES:
patent: 4087535 (1978-05-01), Heubach et al.
patent: 4284786 (1981-08-01), Kammerer et al.
patent: 4351841 (1982-09-01), Kammerer et al.
Chem. Pharm. Bull. (1983), vol. 31, No. 6, pp. 1896-1901.
Chem. Pharm. Bull. (1984), vol. 32, No. 10, pp. 3848-3856.
Chem. Pharm. Bull. (1984), vol. 32, No. 1, pp. 106-116.
Devens Bruce H.
Patterson John W.
Fay Zohreh A.
Freyberg Derek P.
Moran Tom M.
Roth Carol J.
Syntex (U.S.A.) Inc.
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