Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1982-04-14
1984-03-20
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 64, A61K 3171, C07H 1524
Patent
active
044381050
ABSTRACT:
Starting from the known 4'-deoxy-4'-iodo-N-trifluoroacetyldaunorubicin, two new anthracycline glycosidic antibiotics, the 4'-deoxy-4'-iodo-daunorubicin and 4'-deoxy-4'-iodo-doxorubicin, have been prepared by known procedures. Both the new glycosides have been found to be endowed with outstanding antitumoral activity.
REFERENCES:
patent: 4303785 (1981-12-01), Umezawa et al.
patent: 4345070 (1982-08-01), Suarato et al.
Arcamone Federico
Casazza Anna M.
Penco Sergio
Suarato Antonino
Brown Johnnie R.
Farmaitalia Carlo Erba S.p.A
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