4-iminoquinolines, processes for their preparation, and their us

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514278, 546 15, 546158, A61K 3147, C07D21504, C07D21512, C07D21516

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active

056021461

ABSTRACT:
Compounds of the formula I ##STR1## and tautomeric forms thereof, of the formula Ia, ##STR2## in which the substituents R1-R4 and X and Y have the meanings given; have an antiviral activity.

REFERENCES:
A. Desvignes et al., Recherche sur les Aminoquinoleines. XVIII. Activite antibacterienne et antifongique in vitro d'alkylamino-4 quinoleines a longues chaines (5.sup.e memoire), Annales Pharmaceutiques Francaises, 35(7-8):239-247 (1977).
P. Rajamanickam et al., A New Synthesis of Dictamnine, Evolitrine & 6-Methyldictamnine, Indian Journal of Chemistry, vol. 26B:910-913 (Oct. 1987).
R. Hull et al., Reactions of Heterocycles with Thiophosgene. Part V. 7-Chloro-1,2-1,2-dihydro-4-methoxy-2-thioxoquinoline-3-carbaldehyde, a Prodct from 7-Chloro-4-methoxyquinoline, J. Chemical Society Trans 1, 22:2271-2280 (1975).
S. Renault et al., Recherche sur les Aminoquinoleines, XVI: alkylamino-4 quinoleines et quinaldines a longues chaines a activite amoebicide potentielle (4.sup.e memorie): influence de substituants nucleaires electrodonneurs, Eur. J. Med. Chem., 11(6):561-565 (1976).
Abstract of Study of Aminquinolines, XVI: Long-Chain 4-alkylaminoquinolines and Quinaldines with Potential Amebicide Activity. Part 4: Effect of Nuclear Electron Donor Substituents, CA87(3):22980t, 1976.
Abstract of Aminoquinolines. XVIII. In Vitro Antibacterial and Antifungal Activity of Long Chain 4-alkyaminoquinolines, CA88(13):83971h, 1977.
Abstract of NZ 220168, Mochida et al., "1-Acyl-2-3-Dihydro-4(1H)-Quinolinone-4-Oxime Derivatives", New Zealand Patent Office Journal, No. 1329, vol. 79, Issue No. 1, published Feb. 26, 1990.
"Formation of Homopiperazine Rings by the Lithium Aluminum Hydride Catalyzed Rearrangement of Some Piperidone Oximes in the Phenothiazine Series", Harfenist et al., J. Amer. Chem. Soc., 80:6080-6083(1958).
"Synthetic Studies on Pyrroloquinolines, Part IV. Preparation of Hydrogenated 3a-Methylpyrrolo[3,2-c]quinolines", Tanaka et al., J. C. S. Perkin I, 2110-2113(1974).
"Ring Closure of 3-Acetyl-4-azido-2-quinolones to Isoxazolor[4,3-c]quinolones", Roschger et al., Liebigs Ann. Chem., 821-823(1990).
"Thermal Cyclization of 4-Azido-3-formyl-2-quinolones to Isoxazolo[4,3-c]quinolones", Roschger et al., Liebigs Ann. Chem., 401-403(1991).
".beta.-Amino Ketones. Synthesis and Some Biological Activities in Mice of 3,3-Dialkyl-1,2,3,4-tetrahydro-4-quinolinones and Related Mannich Bases", Daruwala et al., Journal of Medicinal Chemistry, 17(8):819-824(1974).
"The Chemistry of Isatoic Anhydride", Coppola, G. M., Synthesis, 505-536 (1980).
C. Podesva et al, "Synthesis and Chemistry . . . ", Canadian J. of Chem, 46, 435-439, 1968.

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