4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat an

Details 4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat an 4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat an

1976-05-26

1978-04-11

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548302, C07D48704, A61K 31415

Patent

active

040839877

ABSTRACT:
4-Imino-1,3-diazabicyclo[3.1.0]-hexan-2-one of one or more of the tautomeric formulas ##STR1## or a physiologically compatible salt thereof exhibits cancerostatic and immuno-stimulant activity. It is produced by cyclized 1-carboxamido-2-cyanoaziridine in an anhydrous polar organic solvent in the presence of a catalytic amount of an alkali.

REFERENCES:
hillers et al. Chem. Abst. 1972, vol. 76, No. 126,824j.

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