4-Hydroxycoumarins

Details 4-Hydroxycoumarins 4-Hydroxycoumarins

1974-05-22

1976-05-18

Patten, James A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260473A, 260515R, 260618D, 260618F, 424281, 260590R, C07D31156

Patent

active

039578240

ABSTRACT:
Novel 4-hydroxy coumarins substituted in the 3 position with substituted tetrahydronaphthyl groups are described. A method of making them by condensing 4-hydroxy coumarin with hydroxyl or halogeno derivatives of the substituted tetrahydronaphthalenes is described. The compounds of the invention are potent anticoagulants finding typical uses as rodenticides. As rodenticides they are particularly effective against rodents resistant to such agents as Warfarin, Coumatetralyl, Diphacinone and Pival.

REFERENCES:
patent: 2872457 (1959-02-01), Schroeder et al.
patent: 2952689 (1960-09-01), Enders et al.
Weygand Preparative Organic Chem. (1972), p. 222.

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