4-hydroxycoumarin derivatives

Details 4-hydroxycoumarin derivatives 4-hydroxycoumarin derivatives

1986-12-16

1988-05-31

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549285, C07D31112, A61K 3135

Patent

active

047481854

ABSTRACT:
The invention provides 4-hydroxycoumarin compounds of general formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from hydrogen and halogen atoms and R represents a group of formula ##STR2## wherein one of n and n' is O, the other being 0 or 1, D represents a moiety --O--, --(CH.sub.2).sub.m -- or --O(CH.sub.2).sub.m -- where m is 1 or 2 and X represents a substituent selected from hydrogen, halogen, CN, CF.sub.3, OCF.sub.3, C.sub.1-6 alkyl and C.sub.1-6 alkoxy moieties, provided that when n is 1 and D is --OCH.sub.2 --, X may additionally represent a phenyl group, optionally substituted in the 4-position by a substituent selected from halogen, CN, CF.sub.3, OCF.sub.3, C.sub.1-6 alkyl and C.sub.1-6 alkoxy moieties; their preparation and their use as rodenticides.

REFERENCES:
patent: 2427578 (1947-09-01), Stahmann et al.
patent: 3957824 (1976-05-01), Hadler et al.
patent: 4520007 (1985-05-01), Entwistle et al.

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