4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and

Details 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and

1977-06-29

1978-12-05

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546123, A61K 31435, C07D47104

Patent

active

041286499

ABSTRACT:
Anti-allergic 4-hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters are prepared by reacting a 3,4-dihydro-1,3-dioxo-1H-pyrido[2,3-d][1,3]oxazine (a 3-azaisatoic anhydride) with an alkali metal salt of a malonic ester.

REFERENCES:
patent: 3506667 (1970-04-01), Kaminsky
patent: 3590036 (1971-06-01), Lesher et al.
patent: 3761592 (1973-09-01), Mizzoni et al.
patent: 3772301 (1973-11-01), VON Strandtmann et al.
patent: 3853864 (1974-12-01), Santilli et al.
patent: 3960868 (1976-06-01), Ferrini et al.
patent: 3963736 (1976-06-01), Nakagome et al.
patent: 4048182 (1977-09-01), Denzel et al.
Buckle et al., J. Medicinal Chem., vol. 18, pp. 726-732 (L) (1975).
Mitscher et al., Heterocycles, vol. 3, No. 11, pp. 913-919 (1975).
Zasshi et al., Jour. of the Pharmaceutical Soc. of Japan, vol. 71, pp. 1100-1112 (1951).

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