Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-07-14
1999-03-30
MacMillan, Keith D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514327, 5463401, 546366, 546370, C07D21100, A01N 4340
Patent
active
058890262
ABSTRACT:
The present invention relates to compounds of the formula ##STR1## wherein x is --O--, --NH--, --CH.sub.2 --, --CH.dbd., --CO.sub.2 --, --CONH--, --CON(lower alkyl)--, --S-- and --SO.sub.2 --;
REFERENCES:
Chemical Abstracts AN 1973:43277, Mauyama et al., Dec. 1972.
Chenard, B.L., et al., J. Med. Chem., 34(10):3085-3090 (1991).
Derwent Abstract of FR 2,672,286 (corresponds to Document B4), (Aug. 7, 1992).
Derwent Abstract of FR 2,681,319 (corresponds to Document B5), (Mar. 19, 1993).
Green, T., Protective Groups in Organic Synthesis Chapter 7, John Wiley & Sons, Inc. (1981) pp. 218-287.
Hollmann & Heinemann, (1994) Annu. Rev. Neurosci. 17:31.
Sigel, et al., J. Biol. Chem. 269:8204 (1994).
Malherbe, et al., Mol. Brain Res. 8:199 (1990).
Methfessel et al., Pflugers Arch. 407:577 (1986).
Alanine Alexander
Buttelmann Bernd
Heitz Neidhart Marie-Paule
Pinard Emmanuel
Wyler Rene
Hoffmann-La Roche Inc.
Johnston George W.
Kass Alan P.
MacMillan Keith D.
Tramaloni Dennis P.
LandOfFree
4-hydroxy-piperodine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 4-hydroxy-piperodine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-hydroxy-piperodine derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1215475