4-Hydroxy-naphthpyridine-2(1H)-one-3-carboxylic acids and esters

Details 4-Hydroxy-naphthpyridine-2(1H)-one-3-carboxylic acids and esters 4-Hydroxy-naphthpyridine-2(1H)-one-3-carboxylic acids and esters

1978-03-13

1979-10-02

Wheeler, David

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546110, 544 89, A61K 3147, C07D22106

Patent

active

041698932

ABSTRACT:
Anti-allergic 4-hydroxy-naphthpyridine-2(1H)-one-3-carboxylic acids and esters are prepared by reacting a 1,3-dioxo-1-naphth[4,5-b]oxazine with an alkali metal salt of a malonic ester (and hydrolyzing to obtain the acids).

REFERENCES:
patent: 3960868 (1976-06-01), Ferrini et al.
patent: 3966743 (1976-06-01), Berger et al.
patent: 4065457 (1977-12-01), Buckle et al.
DeGroot, "Journ. Org. Chem.", vol. 31, pp. 3954-3958 (1966).

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