4-hydroxy-5,6-dihydro-1 H -pyridin-2-one compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S012000, C544S013000

Reexamination Certificate

active

07834009

ABSTRACT:
The invention is directed to 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds of Formula I and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus:wherein R6isX is N,Ring A is a 5- or 6-membered aryl, optionally substituted by 1-3 R8moieties,n is 2, andR1-R6and R8are defined herein.

REFERENCES:
patent: 7582626 (2009-09-01), Tran et al.
patent: 2005/0153877 (2005-07-01), Miao et al.
patent: 2006/0040927 (2006-02-01), Blake et al.
patent: 2006/0189602 (2006-08-01), Zhou et al.
patent: 2006/0211695 (2006-09-01), Borzilleri et al.
patent: 2006/0252785 (2006-11-01), Blake et al.
patent: WO-01/85172 (2001-11-01), None
patent: WO-02/098424 (2002-12-01), None
patent: WO-03/059356 (2003-07-01), None
patent: WO-2006115221 (2006-11-01), None
Vippagunta et al. “Crystalline Solids,” Advanced Drug Delivery Reviews, 2001, 48, pp. 3-26).
U.S. Appl. No. 11/766,668, Ellis et al.
U.S. Appl. No. 11/898,334, Zhou et al.
U.S. Appl. No. 11/861,678, Dragovich et al.
U.S. Appl. No. 11/955,144, Tran et al.
U.S. Appl. No. 11/955,193, Ruebsam et al.
U.S. Appl. No. 12/048,933, Ruebsam et al.
U.S. Appl. No. 12/061,499, Tran et al.
U.S. Appl. No. 11/845,515, Ellis et al.
Int'l Search Report of In'tl Appl. No. PCT/US05/45588.
Tedesco et al., 3-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, J. Med. Chem. 49:971-983 (2006).
Fisyuk et al., Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1 H)-ones by Intramolecular Wittig Reaction. Molecules, Feb. 28, 2002, vol. 7, pp. 124-128.

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